Company Overview

Therametics is a skin therapeutics company that specializes in the development of technology to treat inflammatory skin problems and aging skin.

The company has developed and is continuing to develop a line of novel topical dermatologics to target unmet needs for anti-inflammatory and anti-aging therapeutics.  These unique formulations effectively treat a variety of inflammation-based skin problems, reduce the deterioration of and restore youthfulness to aging skin, regulate human skin pigmentation, and generally improve skin appearance and function. Therametics develops topical products for the OTC drug market and for the rapidly growing “cosmeceutical” (bioactive cosmetics) market. Therametics also develops topical dermatologics for the prescription drug market and commercializes these through licensing relationships with pharmaceutical partners.

Therametics was founded in 2006 by Dr. Bryan Fuller, a professor and skin biochemistry researcher at the University of Oklahoma Health Sciences Center for 21 years.  Therametics’ corporate offices and laboratories are located in the Research Park in Oklahoma City.The company’s molecular biology based drug discovery program has identified several chemical compounds that display potent anti-inflammatory and anti-aging activities. The company’s lead compound is trademarked, Therosol®.  This compound and other structurally related compounds have been shown, in clinical studies, to be effective in treating a variety of inflammatory skin problems including rosacea, seborrheic dermatitis, psoriasis, radiation dermatitis, and hyperpigmentation. Patent applications, including PCT, have been filed to protect the dermatological use of these compounds.To deliver Therosol®  and related “bioactives” across the skin’s surface and down to damaged and inflamed target cells in the epidermis and dermis, Therametics has developed a proprietary topical formulation system, called Bioactive Phase Partitioning. This novel formulation design sequesters Therosol® and other “bioactives” into microscopic oil droplets which are dispersed throughout a silicone-based serum. When the serum is applied to the skin, the “bioactive” in these droplets is released onto the skin’s surface at a high concentration. This phase specific enrichment accelerates the penetration of the “actives’” into the skin.